Author B Robinson

 Objectives

 1.                To review how the body’s immune system responds to Tuberculosis and why it fails to eradicate it.

2.                To review the clinical patterns of the disease, particularly those present in the lung.

3.                To discuss strategies for screening and diagnosis.

4.                To review the epidemiology of TB, in particular the following issues:

a)               how and why the incidence has changed over the past century, particularly from the points of view of nutrition and therapy.

b)               To discuss the re-emergence of TB, particularly in HIV- affected countries.

5.                To discuss health budgeting in an HIV-affected region in Africa from the perspective of  TB screening & therapy using case examples.

 Outline

·        Host immune response to TB

·        Clinical patterns of disease

·        Epidemiology of TB

·        Health problem solving in a developing nation

 Questions

1.                Which components of the host immune system are most important in defence against tuberculosis?

2.                What are the major pulmonary manifestations of TB?

3.                In what way can a diagnosis of tuberculosis be made?

4.                What is the standard therapy for tuberculosis?

5.                What factors over the past century have altered the incidence of tuberculosis in our community?

6.                Given a limited budget, what is the most efficient way to detect and eradicate tuberculosis in poor rural areas?

Web microbiology/Tb lecures

 http://www.uic.edu/depts/mcmi/restricted/med/mim426/jc/jclec26.html

http://www-medlib.med.utah.edu/WebPath/TUTORIAL/MTB/MTB.html

http://www.hopkins-id.edu/diseases/tb/tb_bishai.html

http://hopkins-id.edu/diseases/tb/tb_treat.html

http://www.noah.cuny.edu/tb/nycdoh/nycdohtb1.html (lay descriptions from new york)

http://www-micro.msb.le.ac.uk/MBChB/6c.html

http://www.eda.org.hk/medurl.htm (lists lots of internet medical stuff)

Internet Tb resources (mostly centres of excellence or national information organisations)

http://bubl.ac.uk/link/t/tuberculosis.htm

http://www.cdcnpin.org/

http://www.lungusa.org/diseases/

http://www.lungnet.org.au/

http://www.njc.org/

http://molepi.stanford.edu/tb.www.html

http://www.brown.edu/Research/TB-HIV_Lab/

And nothing to do with Tb

 http://www.music.mcgill.ca/auscultation/the_heart.html  (heart and lung sounds on line).

http://www.hsc.virginia.edu/med-ed/otherMedEd.html (medical software available from lots of medical schools).

TB CPC powerpoint slides